What is LPS in bacteria?
Abstract. Bacterial lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans.
What is LPS also known as?
One of the most studied bacterial surface molecules is the glycolipid known as lipopolysaccharide (LPS), which is produced by most Gram-negative bacteria.
Do humans have LPS?
Notably, gram-negative bacteria, the source of LPS, are known to colonize the gastrointestinal tract of even apparently healthy individuals20. Indeed, the human gut is a major reservoir of LPS and, for these endotoxins, an important site of entry to the systemic circulation.